Beate Ritz

Professor

Faculty

britz@ucla.edu

310.206.7458, 310.206.6039

73-320A CHS CAMPUS- 177220

Academic Titles/Accomplishments/Affiliations:

PhD., Epidemiology, School of Public Health, UCLA
Doctoral Degree in Medical Sociology, University of Hamburg.
MD., Medical Examination Certificate, Registration as a Physician

Research interest:

Her research focuses on the health effects of occupational and environmental toxins such as pesticides, ionizing radiation, and air pollution on chronic diseases including neurodegenerative and neurodevelopmental disorders (Parkinson’s disease, autism cognition), cancers, and adverse birth outcomes and asthma. She previously investigated the causes of cancer in chemical toxin and radiation exposed workers and assessed the impact of ergonomic work-place factors on musculo-skeletal disorders. For the past two decades, she studied the effects of air pollution on adverse birth outcomes as well as asthma, autism, and cancers in children in Southern California. In 2006, she received the Robert M Zweig Memorial award for outstanding achievement in air quality and medicine from the South Coast Air Quality Management District and in 2012 she has been appointed a member of the CA-EPA Scientific Review Panel on Toxic Air Contaminants. Since 1997, she has been investigating the long-term effects of pesticide exposures on Parkinson’s disease and cancers and is currently conducting a project to implement a Parkinson’s disease registry required by a 2004 law in California. In 2011 she recieved an award from the American Parkinson’s Disease Association (APDA) for outstanding contributions to the advancement of Parkinsons research. In her research she uses geographic information system (GIS) modeling of environmental exposures including pesticide use and traffic related air pollution in California and investigates links between genetic susceptibility factors and environmental exposures in populations. She is directing and collaborating in a large number of federally (NIH, DOD), state (California Air Resources Board), and foundation (Michael J Fox Foundation, Komen) funded research projects.

Beate Ritz joined the faculty of the School of Public Health at UCLA in 1995 and is currently Professor and Vice Chair of the Epidemiology Department and holds co-appointments in the Environmental Health department at the UCLA School of Public Health and in Neurology, UCLA School of Medicine; she is a member of the Center for Occupational and Environmental Health (COEH), the Southern California Environmental Health Science Center (SCEHSC), and co-directs the NIEHS-funded UCLA Center for Gene-Environment Studies of Parkinson’s disease. Dr. Ritz received her MD and a PhD in Medical Sociology from the University of Hamburg Germany in 1983 and 1987; she was a research fellow and resident at the Psychiatric University-Hospital in Hamburg from 1987-1989, and received doctoral training and a PhD degree in Epidemiology in 1995 from UCLA.

Publications

Ozone Exposure, Outdoor Physical Activity, and Incident Type 2 Diabetes in the SALSA Cohort of Older Mexican Americans Yu, Y., Jerrett, M., Paul, K. C., Su, J., Shih, I. F., Wu, J., ... & Ritz, B. (2021). Environmental Health Perspectives, 129(9), 097004.
Residential proximity to pesticide application as a risk factor for childhood central nervous system tumors Lombardi, C., Thompson, S., Ritz, B., Cockburn, M. and Heck, J.E. (2021). Environmental Research, 197, p.111078.
α-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson’s disease from multiple system atrophy Dutta, S., Hornung, S., Kruayatidee, A., Maina, K.N., Del Rosario, I., Paul, K.C., Wong, D.Y., Folle, A.D., Markovic, D., Palma, J.A. Serrano, G.E.,... Ritz, B, and Bitan, G.. (2021). Acta Neuropathologica, pp.1-17.
Metabolomics analysis of maternal serum exposed to high air pollution during pregnancy and risk of autism spectrum disorder in offspring. Kim, J. H., Yan, Q., Uppal, K., Cui, X., Ling, C., Walker, D. I., … & Ritz, B. (2021). Environmental Research, 110823.
High-Resolution Metabolomic Assessment of Pesticide Exposure in Central Valley, California. Yan, Q., Paul, K.C., Walker, D.I., Furlong, M.A., Del Rosario, I., Yu, Y., Zhang, K., Cockburn, M.G., Jones, D.P. and Ritz, B.R. (2021). Chemical Research in Toxicology. https://doi.org/10.1021/acs.chemrestox.0c00523
Parental occupation and childhood germ cell tumors: a case–control study in Denmark, 1968–2016. Hall, C., Hansen, J., Olsen, J., He, D., von Ehrenstein, O.S., Ritz, B. and Heck, J.E. Cancer Causes & Control, pp.1-10.
Social stress and risk of declining cognition: a longitudinal study of men and women in the United States. Lindert, J., Paul, K.C., Margie, E.L., Ritz, B. and Seeman, T. Social Psychiatry and Psychiatric Epidemiology, pp.1-10.
DNA methylation biomarker for cumulative lead exposure is associated with Parkinson’s disease. Paul, K. C., Horvath, S., Del Rosario, I., Bronstein, J. M., & Ritz, B. (2021). Clinical Epigenetics, 13(1), 1-4.
Parental Occupation and Risk of Childhood Retinoblastoma in Denmark. Omidakhsh, N., Hansen, J., Ritz, B., Coleman, A. L., McKean-Cowdin, R., Olsen, J., & Heck, J. E. (2021). Journal of Occupational and Environmental Medicine, 63(3), 256-261.
Universal DNA methylation age across mammalian tissues. Lu, A. T., Fei, Z., Haghani, A., Robeck, T. R., Zoller, J. A., Li, C. Z., Ritz, B. R., … & Horvath, S. (2021). bioRxiv.
Low HbA1c levels and all-cause or cardiovascular mortality among people without diabetes: the US National Health and Nutrition Examination Survery 1999-2015. Inoue, K., Nianogo, R., Telesca, D., Goto, A., Khachadourian, V., Tsugawa, Y., … & Ritz, B. (2020). International Journal of Epidemiology.
Analysis of epidemiologic study data when there is a geolocation uncertainty. Langholz, B., Escobedo, L. A., Goldberg, D. W., Heck, J. E., Thompson, L. K., Ritz, B., & Cockburn, M. (2020). Spatial Statistics, 100486.
Ambient Pyrethroid Pesticide Exposures in Adult Life and Depression in Older Residents of California’s Central Valley. Furlong, M. A., Paul, K. C., Cockburn, M., Bronstein, J., Keener, A., Del Rosario, I., … & Ritz, B. (2020). Environmental Epidemiology (Philadelphia, Pa.), 4(6).
Metabolic dysfunction modifies the influence of traffic-related air pollution and noise exposure on late-life dementia and cognitive impairment: A cohort study of older Mexican-Americans. Yu, Y., Haan, M., Paul, K. C., Mayeda, E. R., Jerrett, M., Wu, J., … & Ritz, B. R. (2020). Environmental Epidemiology, 4(6), e122.
Behavioral Problems at Age 11 Years After Prenatal and Postnatal Exposure to Acetaminophen: Parent-reported and Self-reported Outcomes. Inoue, K., Ritz, B., Ernst, A., Tseng, W. L., Yuan, Y., Meng, Q., … & Liew, Z. (2020).
Air Pollution, Cardiovascular Disease, and Dementia. Inoue K, Paul K.C., Ritz B.R. JAMA Neurol. 2020;77(12):1580.
Traffic-Related Noise Exposure and Late-life Dementia and Cognitive Impairment in Mexican-Americans. Yu Y, Mayeda ER, Paul KC, Lee E, Jerrett M, Su J, Wu J, Shih IF, Haan M, Ritz B. Epidemiology. 2020 Aug 3.
Mediation of the Associations of Physical Activity With Cardiovascular Events and Mortality by Diabetes in Older Mexican Americas. Inoue, K., Mayeda, E. R., Paul, K. C., Shih, I. F., Yan, Q., Yu, Y., … & Ritz, B. R. (2020). American Journal of Epidemiology, 189(10), 1124-1133.
A Survey of Rare Epigenetic Variation in 23,116 Human Genomes Indentifies Disease-Relevant Epivariations and CGG Expansions. Garg, P., Jadhav, B., Rodriguez, O. L., Patel, N., Martin-Trujillo, A., Jain, M., Ritz, B… & Sharp, A. J. (2020). The American Journal of Human Genetics, 107(4), 654-669.
Epigenetic mutation load is weakly correlated with epigenetic age acceleration. Yan, Q., Paul, K. C., Lu, A. T., Kusters, C., Binder, A. M., Horvath, S., & Ritz, B. (2020). Aging (Albany NY), 12(18), 17863.
Maternal Prenatal Smoking and Autism Spectrum Disorder in Offspring: a California Statewide Cohort and Sibling Study. von Ehrenstein, O. S., Cui, X., Yan, Q., Aralis, H., & Ritz, B. (2020). American Journal of Epidemiology.
Traffic-Related Air Pollution and Incident Dementia: Direct and Indirect Pathways Through Metabolic Dysfunction. Paul KC, Haan M, Yu Y, Inoue K, Mayeda ER, Dang K, Wu J, Jerrett M, Ritz B. Journal of Alzheimer’s Disease. 2020 Jul 8(Preprint):1-5.
Air Pollution and Adverse Pregnancy and Birth Outcomes: Mediation Analysis Using Metabolomic Profiles. Inoue K, Yan Q, Arah OA, Paul K, Walker DI, Jones DP, Ritz B. Current Environmental Health Reports. 2020 Aug 8:1-2.
An epigenome-wide association study of ambient pyrethroid pesticide exposures in California’s central valley. Furlong MA, Paul KC, Yan Q, Chuang YH, Cockburn MG, Bronstein JM, Horvath S, Ritz B. International Journal of Hygiene and Environmental Health. 2020 Aug 1;229:113569.
Predicting Ambient Exposure to Agricultural Pesticides during Pregnancy and Risk of Cerebral Palsy: A Population-Based Study in California Liew Z, von Ehrenstein OS, Ling C, Yuan Y, Meng Q, Cui X, Park AS, Uldall P, Olsen J, Cockburn M, Ritz B. Toxics. 2020 Sep;8(3):52.
Genetic risk scores and hallucinations in patients with Parkinson disease. Kusters CD, Paul KC, Folle AD, Keener AM, Bronstein JM, Dobricic V, Tysnes OB, Bertram L, Alves G, Sinsheimer JS, Lill CM, Maple-Grodem J, Ritz B. Neurology Genetics. 2020 Oct 1;6(5).
Untargeted Metabolomics Screen of Mid-pregnancy Maternal Serum and Autism in Offspring. Ritz B, Yan Q, Uppal K, Liew Z, Cui X, Ling C, Inoue K, von Ehrenstein O, Walker DI, Jones DP. Autism Research. 2020 Jun 4.
Untargeted Metabolomics Screen of Mid-pregnancy Maternal Serum and Autism in Offspring. Ritz, B., Yan, Q., Uppal, K., Liew, Z., Cui, X., Ling, C., … & Jones, D. P. (2020). Autism Research, 13(8), 1258-1269.
SAT-447 Thyroid Function, Cardiovascular Disease, and Mortality: A Mediation Analysis. Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee C, Leung AM. Journal of the Endocrine Society. 2020 Apr;4(Supplement_1):SAT-447.
Spina bifida and pediatric cancers. Heck, J. E., Lee, P. C., Wu, C. K., Li, C. Y., He, D., Federman, N., Ritz, B.R., … & Hansen, J. (2020). Pediatric hematology and oncology, 37(7), 630-636.
Prenatal pesticide exposure and childhood leukemia- A California statewide case-control study. Park AS, Ritz B, Yu F, Cockburn M, Heck JE. International journal of hygiene and environmental health. (2020) May 1;226:113486.
Completeness and Validation of Automated Reporting to the California Parkinson’s Disease Registry (1318) Wu A, Malatt C, Truong B, Wu W, Bryant-Dunmire K, Agosta F, Ritz B, Tanner C, Cheng E. Neurology. 2020 April 14; 95 (15 Supplement)
Pretirm Birth among Infants Exposed to in Utero Ultrafine Particles from Aircraft Emissions. Wing SE, Larson TV, Hudda N, Boonyarattaphan S, Fruin S, Ritz B. Environmental Health Perspectives. 2020 Apr 2;128(4):047002.
Association between outdoor air pollution and risk of malignant and benign brain tumors: The Multiethnic Cohort Study Wu AH, Wu J, Tseng C, Yang J, Shariff-Marco S, Fruin S, Larson T, Setiawan VW, Masri S, Porcel J, Jain J, Chen TC, Stram DO, Le Marchand L, Ritz B, Cheng I. JNCI cancer spectrum. 2020 Apr;4(2):pkz107.
The association of short-term effects of air pollution and sleep disorders among elderly residents in China. Tang M, Li D, Liew Z, Wei F, Wang J, Jin M, Chen K, Ritz B. Science of The Total Environment. 2020 Mar 15;708:134846.
Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson’s diesease. Vallerga CL, Zhang F, Fowdar J, McRae AF, Qi T,Nabais MF, Zhang Q, Kassam I, Henders AK, Wallace L, Montgomery G, Chuang Y, Horvath S, Ritz B, Halliday G, Hickie I, … Gratten J. Nature Communications. 11, 1238 (2020).
Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee CM, Leung AM. JAMA Network Open. (2020) Feb 5;3(2):e1920745-.
Gestational risk factors and childhood cancers: a cohort study in Taiwan. Heck JE, Lee PC, Wu CK, Tsai HY, Ritz B, Arah OA, Li CY. International Journal of Cancer. (2020) Feb 5.
Occupational livestock or animal dust exposure and offspring cancer risk in Denmark, 1968-2016. Hall C, Hansen J, von Ehrenstein OS, He D, Olsen J, Ritz B, Heck JE. International Archives of Occupational and Environmental Health. 2020 Feb 5:1-0.
Air pollution, noise exposure, and metabolic syndrome – A cohort study in elderly Mexican-Americans in Sacramento area. Yu Y, Paul K, Arah OA, Mayeda ER, Wu J, Lee E, Shih IF, Su J, Jerrett M, Haan M, Ritz B. (2020) Environment international.
The Effects of Fine Dust, Ozone, and Nitrogen Dioxide on Health Ritz B, Hoffmann B, Peters A. Deutsches Ärzteblatt International. (2019) Dec;116(51-52):881.
Perfluoroalkyl Substances and Maternal Thyroid Hormones in Early Pregnancy; Findings in the Danish National Birth Cohort. Inoue, K., Ritz, B., Andersen, S. L., Ramlau-Hansen, C. H., Høyer, B. B., Bech, B. H., … & Liew, Z. (2019). Environmental health perspectives, 127(11), 117002.
Rapid Cardioversion of Recent-Onset Atrial Fibrillation in the Emergency Department with Vernakalant: Insights from the Multinational Spectrum Registry. Ritz B, Martin A, Merino JL, Bager JE, Domanovits H, Juhlin T, Levy S, Weaver WD, Hartikainen J, Carbajosa J. Circulation. 2019 Nov 19;140(Suppl_1):A15421-.
Hexachlorocyclohexane exposure alters the microbiome of colostrum in Chinese breastfeeding mothers. Tang, M., Xu, C., Chen, K., Yan, Q., Mao, W., Liu, W., & Ritz, B. (2019). Environmental Pollution, 254, 112900.
The Roles of Physical Activity and Inflammation in Mortality, Cognition, and Depressive Symptoms Among Older Mexican Americans. Shih, I. F., Haan, M. N., Paul, K. C., Yu, Y., Sinsheimer, J. S., & Ritz, B. (2019). American journal of epidemiology, 188(11), 1944-1952.
Phototherapy and childhood cancer: shared risk factors. Heck, J. E., Huang, X., Calkins, K. L., Sun, Y., Olsen, J., Ritz, B., & Hansen, J. (2019). International journal of cancer.
Hypertension, antihypertensive medications use and risk of age-related macular degeneration in California Teachers Cohort. Xu, X., Ritz, B., Coleman, A., Liew, Z., Deapen, D., Lee, E., … & Heck, J. E. (2019). Journal of human hypertension, 1-9.
A case-control study of breast cancer risk and ambient exposure to pesticides. Tayour, C., Ritz, B., Langholz, B., Mills, P. K., Wu, A., Wilson, J. P., … & Cockburn, M. (2019). Environmental Epidemiology, 3(5), e070.
High parental occupational social contact and risk of childhood hematopoietic, brain and bone cancers. Omidakhsh, N., Hansen, J., Ritz, B., Olsen, J., & Heck, J. E. (2019). Cancer epidemiology, 62, 101575.
Maternal serum metabolome and traffic-related air pollution exposure in pregnancy. Yan, Q., Liew, Z., Uppal, K., Cui, X., Ling, C., Heck, J. E., … & Ritz, B. (2019). Environment international, 130, 104872.
Cluster-based bagging of constrained mixed-effects models for high spatiotemporal resolution nitrogen oxides prediction over large regions. Li, L., Girguis, M., Lurmann, F., Wu, J., Urman, R., Rappaport, E., Ritz, B. … & Habre, R. (2019). Environment international, 128, 310-323.
Association Between Reported Long Working Hours and History of Stroke in the CONSTANCES Cohort Neuroal and Oligodendroglial Exosomal α-Synuclein Distinguishes Parkinson’s Disease from Multiple System Atrophy. Dutta S, del Rosario I, Paul K, Palma JA, Perlman SL, Poon WW, Kaufmann H, Fogel BL, Bronstein JM, Ritz B, Bitan G. (2019) Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. 15(7):P1345.
Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels. Lee Y, Choufani S, Weksberg R, Wilson SL, Yuan V, Burt A, Marsit C, Lu AT, Ritz B, Bohlin J, Gjessing HK. (2019) Aging.11(12):4238.
Prenatal Exposure to Air Toxics and Malignant Germ Cell Tumors in Young Children. Hall, C., Heck, J. E., Ritz, B., Cockburn, M., Escobedo, L. A., & von Ehrenstein, O. S. (2019). Journal of occupational and environmental medicine, 61(6), 529-534.
Residential mobility in early childhood and the impact on misclassification in pesticide exposures. Ling, C., Heck, J. E., Cockburn, M., Liew, Z., Marcotte, E., & Ritz, B. (2019). Environmental Research.
Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia: a population-based study. Heck, J. E., He, D., Contreras, Z. A., Ritz, B., Olsen, J., & Hansen, J. (2019). Occupational and environmental medicine, oemed-2019.
Longitudinal Epigenome-Wide Methylation Study of Cognitive Decline and Motor Progression in Parkinson’s Disease. Chuang, Y. H., Lu, A. T., Paul, K. C., Folle, A. D., Bronstein, J. M., Bordelon, Y., … & Ritz, B. (2019). Journal of Parkinson’s disease, 1-12.
Clinical progression in Parkinson’s disease with features of REM sleep behavior disorder: A population-based longitudinal study. Folle, A. D., Paul, K. C., Bronstein, J. M., Keener, A. M., & Ritz, B. (2019). Parkinsonism & related disorders, 62, 105-111.
Genetic variants in nicotinic receptors and smoking cessation in Parkinson’s disease. Chuang, Y. H., Paul, K. C., Sinsheimer, J. S., Bronstein, J. M., Bordelon, Y. M., & Ritz, B. (2019). Parkinsonism & related disorders, 62, 57-61.
The Association of Gut Microbiome Composition and Parkinson’s Disease in Patient Cohort of Central California. Chou, H. C. L., Lagishetty, V., Bronstein, J., Jacobs, J., & Ritz, B. (2019). Neurology, 92 (15 Supplement), 8-039.
Ambient Air Pollution, Noise, and Late-Life Cognitive Decline and Dementia Risk. Paul, K. C., Haan, M., Mayeda, E. R., & Ritz, B. R. (2019). Annual review of public health, 40, 203-220.
Cancers Preceding Parkinson’s Disease after Adjustment for Bias in a Danish Population-Based Case-Control Study. Cui, X., Liew, Z., Hansen, J., Lee, P. C., Arah, O. A., & Ritz, B. (2019). Neuroepidemiology, 52(3-4), 136-143.
Association between ambient air pollution and breast cancer risk: The Multiethnic Cohort Study. Cheng, I., Tseng, C., Wu, J., Yang, J., Conroy, S. M., Shariff‐Marco, S., … Ritz, B., & Whittemore, A. (2019). International Journal of Cancer.
Healthy Air, Healthy Brains: Advancing Air Pollution Policy to Protect Children’s Health. Payne-Sturges, D. C., Marty, M. A., Perera, F., Miller, M. D., Swanson, M., Ellickson, K., Cory-Slechta, D.A., Ritz, B.… & Talbott, E. O. (2019). American journal of public health, 109(4), 550-554.
High Birth Weight, Early UV Exposure, and Melanoma Risk in Children, Adolescents, and Young Adults. Wojcik, K. Y., Escobedo, L. A., Wysong, A., Heck, J. E., Ritz, B., Hamilton, A. S., … & Cockburn, M. G. (2019). Epidemiology, 30(2), 278-284.
Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study. von Ehrenstein, O. S., Ling, C., Cui, X., Cockburn, M., Park, A. S., Yu, F., … & Ritz, B. (2019). BMJ, 364, l962.
The association between lifestyle factors and Parkinson’s disease progression and mortality. Paul, K. C., Chuang, Y. H., Shih, I. F., Keener, A., Bordelon, Y., Bronstein, J. M., & Ritz, B. (2019). Movement Disorders, 34(1), 58-66.
Air pollution and autism in Denmark. Ritz, B., Liew, Z., Yan, Q., Cuia, X., Virk, J., Ketzel, M., & Raaschou-Nielsen, O. (2018). Environmental Epidemiology, 2(4), e028.
Timescales of developmental toxicity impacting on research and needs for intervention. Grandjean, P., Abdennebi‐Najar, L., Barouki, R., Cranor, C. F., Etzel, R. A., Gee, D., Heindel, J.J, Houggard, K.S., Hunt, P., Nawrot, T.S., Prins, G.S., Ritz, B.… & Sunyer, J. (2018). Basic & clinical pharmacology & toxicology.
Fetal programming and Wilms tumor. Heck, J. E., He, D., Janzen, C., Federman, N., Olsen, J., Ritz, B., & Hansen, J. (2019). Pediatric blood & cancer, 66(1), e27461.
NFE2L2, PPARGC1α, and pesticides and Parkinson’s disease risk and progression. Paul KC, Sinsheimer JS, Cockburn M, Bronstein JM, Bordelon Y, Ritz B. Mech Ageing Dev. 2018 Apr 6;173:1-8. doi: 10.1016/j.mad.2018.04.004. PMID: 29630901
Pre-conceptual and prenatal supplementary folic acid and multivitamin intake, behavioral problems, and hyperkinetic disorders: A study based on the Danish National Birth Cohort (DNBC). Virk J, Liew Z, Olsen J, Nohr EA, Catov JM, Ritz B. 2017. Nutr Neurosci. 2017 Mar 9:1-9. doi: 10.1080/1028415X.2017.1290932. PMID:28276257
Carnitine levels and mutations in the SLC22A5 gene in Faroes patients with Parkinson’s disease. Crooks SA, Bech S, Halling J, Christiansen DH, Ritz B, Petersen MS. Neurosci Lett. 2018 May 14;675:116-119. doi: 10.1016/j.neulet.2018.03.064. Epub 2018 Mar 31. PMID: 29614331
Chronic exposure to inhaled, traffic-related nitrogen dioxide and a blunted cortisol response in adolescents. Wing SE, Bandoli G, Telesca D, Su JG, Ritz B. Environ Res. 2018 May;163:201-207. doi:10.1016/j.envres.2018.01.011. 2018.PMID: 29454852
Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease. Paul KC, Schulz J, Bronstein JM, Lill CM, Ritz BR. JAMA Neurol. 2018 Mar 1;75(3):360-366. doi: 10.1001/jamaneurol.2017.4206. PMID: 29340614
Type 2 Diabetes Mellitus and Alzheimer’s Disease: Overlapping Biologic Mechanisms and Environmental Risk Factors. Paul KC, Jerrett M, Ritz B. Curr Environ Health Rep. 2018 Mar;5(1):44-58. doi: 10.1007/s40572-018-0176-1. Review. PMID: 29464502
Parental occupational exposures and the risk of childhood sporadic retinoblastoma: a report from the Children’s Oncology Group. Omidakhsh N, Bunin GR, Ganguly A, Ritz B, Kennedy N, von Ehrenstein OS, Krause N, Heck JE. Occup Environ Med. 2018 Mar;75(3):205-211. doi: 10.1136/oemed-2017-104404. PMID: 29074554
Smoking and Parkinson disease: Evidence for gene-by-smoking interactions. Lee PC, Ahmed I, Loriot MA, Mulot C, Paul KC, Bronstein JM, Ritz B, Elbaz A. Neurology. 2018 Feb 13;90(7):e583-e592. doi: 10.1212/WNL.0000000000004953. PMID: 29352099
Diagnosis, monitoring and prevention of exposure-related non-communicable diseases in the living and working environment: DiMoPEx-project is designed to determine the impacts of environmental exposure on human health. Budnik LT, Adam B, Albin M, Banelli B, Baur X, Belpoggi F, Bolognesi C, Broberg K, Gustavsson P, Göen T, Fischer A, Jarosinska D, Manservisi F, O’Kennedy R, Øvrevik J, Paunovic E, Ritz B, Scheepers PTJ, Schlünssen V, Schwarzenbach H, Schwarze PE, Sheils O, Sigsgaard T, Van Damme K, Casteleyn L. J Occup Med Toxicol. 2018 Feb 5;13:6. doi: 10.1186/s12995-018-0186-9. PMID: 29441119
Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson’s disease. Kusters CDJ, Paul KC, Guella I, Bronstein JM, Sinsheimer JS, Farrer MJ, Ritz BR. Parkinsonism Relat Disord. 2018 Feb;47:39-44. doi: 10.1016/j.parkreldis.2017.11.339. Nov 24. PMID: 29191473
Physical activity modifies the influence of apolipoprotein E ε4 allele and type 2 diabetes on dementia and cognitive impairment among older Mexican Americans. Shih IF, Paul K, Haan M, Yu Y, Ritz B. 2017. Alzheimers Dement. 2017 Jul 8. pii: S1552-5260(17)30234-0. doi: 10.1016/j.jalz.2017.05.005. PMID:28692819
Early Folic Acid Supplement Initiation and Risk of Adverse Early Childhood Respiratory Health: A Population-based Study. Alfonso VH, Bandoli G, von Ehrenstein O, Ritz B. Matern Child Health J. 2018 Jan;22(1):111-119. doi: 10.1007/s10995-017-2360-6. PMID: 28887720
Cognitive decline, mortality, and organophosphorus exposure in aging Mexican Americans. Paul KC, Ling C, Lee A, To TM, Cockburn M, Haan M, Ritz B. Environ Res. 2017 Oct 2;160:132-139. doi: 10.1016/j.envres.2017.09.017. PMID:28982044
Early Folic Acid Supplement Initiation and Risk of Adverse Early Childhood Respiratory Health: A Population-based Study. Alfonso VH, Bandoli G, von Ehrenstein O, Ritz B. 2017. Matern Child Health J. 2017 Sep 8. doi: 10.1007/s10995-017-2360-6. PMID:28887720
Cognitive decline, mortality, and organophosphorus exposure in aging Mexican Americans. Paul KC, Ling C, Lee A, To TM, Cockburn M, Haan M, Ritz B. Environ Res. 2018 Jan;160:132-139. doi: 10.1016/j.envres.2017.09.017. PMID: 28982044
Pooled analysis of the HLA-DRB1 by smoking interaction in Parkinson disease. Chuang YH, Lee PC, Vlaar T, Mulot C, Loriot MA, Hansen J, Lill CM, Ritz B, Elbaz A. Ann Neurol. 2017 Nov;82(5):655-664. doi: 10.1002/ana.25065. PMID:28981958
Parental occupational exposures and the risk of childhood sporadic retinoblastoma: a report from the Children’s Oncology Group Omidakhsh N, Bunin GR, Ganguly A, Ritz B, Kennedy N, von Ehrenstein OS, Krause N, Heck JE Parental occupational exposures and the risk of childhood sporadic retinoblastoma: a report from the Children’s Oncology Group. Occup Environ Med Published Online First: 26 October 2017. doi: 10.1136/oemed-2017-104404 10/26/2017
Organophosphate pesticides and PON1 L55M in Parkinson’s disease progression. Paul KC, Sinsheimer JS, Cockburn M, Bronstein JM, Bordelon Y, Ritz B. Environ Int. 2017 Oct;107:75-81. doi: 10.1016/j.envint.2017.06.018. PMID:28689109
Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, Papanicolaou GJ, Patel CJ, Ritchie MD, Ritz BR, Thomas DC, Wei P, Witte JS. Am J Epidemiol. 2017 Oct 1;186(7):753-761. doi: 10.1093/aje/kwx227. PMID:28978193
Lessons Learned From Past Gene-Environment Interaction Successes. Ritz BR, Chatterjee N, Garcia-Closas M, Gauderman WJ, Pierce BL, Kraft P, Tanner CM, Mechanic LE, McAllister K. Am J Epidemiol. 2017 Oct 1;186(7):778-786. doi: 10.1093/aje/kwx230. Review. PMID: 28978190
Exposure to ambient dichloromethane in pregnancy and infancy from industrial sources and childhood cancers in California. Park AS, Ritz B, Ling C, Cockburn M, Heck JE. Int J Hyg Environ Health. 2017 Oct;220(7):1133-1140. doi: 10.1016/j.ijheh.2017.06.006. PMID:28720343
Occupational pesticide use and Parkinson’s disease in the Parkinson Environment Gene (PEG) study. Narayan S, Liew Z, Bronstein JM, Ritz B. Environ Int. 2017 Oct;107:266-273. doi:10.1016/j.envint.2017.04.010. PMID:28779877
Constrained Mixed-Effect Models with Ensemble Learning for Prediction of Nitrogen Oxides Concentrations at High Spatiotemporal Resolution. Li L, Lurmann F, Habre R, Urman R, Rappaport E, Ritz B, Chen JC, Gilliland FD, Wu J.2017. Environ Sci Technol. 2017 Sep 5;51(17):9920-9929. doi: 10.1021/acs.est.7b01864. PMID:28727456
Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies. Patel CJ, Kerr J, Thomas DC, Mukherjee B, Ritz B, Chatterjee N, Jankowska M, Madan J, Karagas MR, McAllister KA, Mechanic LE, Fallin MD, Ladd-Acosta C, Blair IA, Teitelbaum SL, Amos CI. 2017. Cancer Epidemiol Biomarkers Prev. 2017 Sep;26(9):1370-1380. doi: 10.1158/1055-9965.EPI-17-0459. PMID:28710076
Parkinson’s disease is associated with DNA methylation levels in human blood and saliva. Chuang YH, Paul KC, Bronstein JM, Bordelon Y, Horvath S, Ritz B. 2017. Genome Med. 2017 Aug 30;9(1):76. doi: 10.1186/s13073-017-0466-5. PMID:28851441
Editor’s Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson’s Disease Risk. Sanders LH, Paul KC, Howlett EH, Lawal H, Boppana S, Bronstein JM, Ritz B, Greenamyre JT. 2017. Toxicol Sci. 2017 Jul 1;158(1):188-198. doi: 10.1093/toxsci/kfx086. PMID:28460087
Occupational and recreational physical activity and Parkinson’s disease in Denmark. Shih IF, Starhof C, Lassen CF, Hansen J, Liew Z, Ritz B. 2017. Scand J Work Environ Health. 2017 May 1;43(3):210-216. doi: 10.5271/sjweh.3633. PMID:28319247
Coffee consumption is associated with DNA methylation levels of human blood. Chuang YH, Quach A, Absher D, Assimes T, Horvath S, Ritz B. 2017. Eur J Hum Genet. 2017 May;25(5):608-616. doi: 10.1038/ejhg.2016.175. PMID:28198392
Fertility Treatment and Childhood Epilepsy: A Nationwide Cohort Study. Kettner LO, Kesmodel US, Ramlau-Hansen CH, Bay B, Ritz B, Matthiesen NB, Henriksen TB.2017. Epidemiology. 2017 May;28(3):412-418. doi: 10.1097/EDE.0000000000000618. PMID:28072588
Residential Pesticide Exposures in Pregnancy and the Risk of Sporadic Retinoblastoma: A Report From the Children’s Oncology Group. Omidakhsh N, Ganguly A, Bunin GR, von Ehrenstein OS, Ritz B, Heck JE. 2017. Am J Ophthalmol. 176:166-173. doi: 10.1016/j.ajo.2017.01.016. PMID:28131887
Maternal Preeclampsia and Odds of Childhood Cancers in Offspring: A California Statewide Case-Control Study. Xu X, Ritz B, Cockburn M, Lombardi C, Heck JE. 2017. Paediatr Perinat Epidemiol. 2017 Mar;31(2):157-164. doi: 10.1111/ppe.12338. PMID:28124497
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors. Quach A, Levine ME, Tanaka T, Lu AT, Chen BH, Ferrucci L, Ritz B, Bandinelli S, Neuhouser ML, Beasley JM, Snetselaar L, Wallace RB, Tsao PS, Absher D, Assimes TL, Stewart JD, Li Y, Hou L, Baccarelli AA, Whitsel EA, Horvath S. 2017. Aging (Albany NY). 9(2):419-446. doi: 10.18632/aging.101168. PMID:28198702
Risk of malignant childhood germ cell tumors in relation to demographic, gestational, and perinatal characteristics. Hall C, Ritz B, Cockburn M, Davidson TB, Heck JE. 2017. Cancer Epidemiol. 2017 Feb;46:42-49. doi: 10.1016/j.canep.2016.12.002. PMID:28013088
Residential pesticide exposures in pregnancy and the risk of sporadic retinoblastoma: a report from the Children’s Oncology Group. Omidakhsh N, Ganguly A, Bunin GR, von Ehrenstein OS, Ritz B, Heck JE. 2017. American Journal of Ophthalmology.
A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Thurston GD, Kipen H, Annesi-Maesano I, Balmes J, Brook RD, Cromar K, De Matteis S, Forastiere F, Ritz B, Samet JM, Sandstrom T, Sigsgaard T, Sunyer J, Brunekreef B. 2017. Eur Respir J. 2017 Jan 11;49(1). pii: 1600419. doi: 10.1183/13993003.00419-2016. PMID:28077473
Fetal growth and air pollution – A study on ultrasound and birth measures. Malmqvist E, Liew Z, Källén K, Rignell-Hydbom A, Rittner R, Rylander L, Ritz B. 2017. Environ Res. 152:73-80. doi: 10.1016/j.envres.2016.09.017. PMID:27741452
Paracetamol use during pregnancy and attention and executive function in offspring at age 5 years. Liew Z, Bach CC, Asarnow RF, Ritz B, Olsen J. 2016. Int J Epidemiol. 45(6):2009-2017. doi: 10.1093/ije/dyw296. PMID:28031314
Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson’s disease. Gatto NM, Paul KC, Sinsheimer JS, Bronstein JM, Bordelon Y, Rausch R, Ritz B. 2016. J Neurol Sci. 370:100-106. doi: 10.1016/j.jns.2016.09.013. PMID:27772736
Prenatal Use of Acetaminophen and Child IQ: A Danish Cohort Study. Liew Z, Ritz B, Virk J, Arah OA, Olsen J. 2016. Epidemiology. 27(6):912-8. doi: 10.1097/EDE.0000000000000540. PMID:27479646
Gene-environment interactions linking air pollution and inflammation in Parkinson’s disease. Lee PC, Raaschou-Nielsen O, Lill CM, Bertram L, Sinsheimer JS, Hansen J, Ritz B. 2016. Environ Res. 151:713-720. doi: 10.1016/j.envres.2016.09.006. PMID:27640071
Traffic-related air pollution increased the risk of Parkinson’s disease in Taiwan: A nationwide study. Lee PC, Liu LL, Sun Y, Chen YA, Liu CC, Li CY, Yu HL, Ritz B. 2016. Environ Int. 2016 Nov;96:75-81. doi: 10.1016/j.envint.2016.08.017. PMID:27614945
Maternal pre-pregnancy and gestational diabetes, obesity, gestational weight gain, and risk of cancer in young children: a population-based study in California. Contreras ZA, Ritz B, Virk J, Cockburn M, Heck JE. 2016. Cancer Causes Control. 27(10):1273-85. doi: 10.1007/s10552-016-0807-5.
Prenatal Maternal Stress and the Risk of Lifetime Wheeze in Young Offspring: An Examination by Stressor and Maternal Ethnicity. Bandoli G, von Ehrenstein O, Ghosh JK, Flores ME, Dunkel Schetter C, Ritz B. 2016. J Immigr Minor Health. 18(5):987-95. doi: 10.1007/s10903-015-0269-y. PMID:26343048
Gene-environment interactions linking air pollution and inflammation in Parkinson’s disease. Lee PC, Raaschou-Nielsen O, Lill CM, Bertram L, Sinsheimer JS, Hansen J, Ritz B. 2016. Environ Res. 151:713-720. doi: 10.1016/j.envres.2016.09.006.
Traffic-related air pollution increased the risk of Parkinson’s disease in Taiwan: A nationwide study. Lee PC, Liu LL, Sun Y, Chen YA, Liu CC, Li CY, Yu HL, Ritz B. 2016. Environ Int. 96:75-81. doi: 10.1016/j.envint.2016.08.017.
Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study. Liew Z, Ritz B, Virk J, Olsen J. 2016. Autism Res. 9(9):951-8. doi: 10.1002/aur.1591. PMID:26688372
The Influence of Pre-natal Supplement Initiation on Preterm Birth Among Majority Hispanic Women in Los Angeles County: The Role of Nativity. Alfonso VH, vonEhrenstein O, Bandoli G, Ritz B. 2016. Matern Child Health J. 20(9):1861-8. doi: 10.1007/s10995-016-1990-4.
Synergistic effects of air pollution and psychosocial stressors on adolescent lung function. Bandoli G, von Ehrenstein O, Ghosh JK, Ritz B. 2016. J Allergy Clin Immunol. 138(3):918-920.e4. doi: 10.1016/j.jaci.2016.04.012.
Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease. Hill-Burns EM, Ross OA, Wissemann WT, Soto-Ortolaza AI, Zareparsi S, Siuda J, Lynch T, Wszolek ZK, Silburn PA, Mellick GD, Ritz B, Scherzer CR, Zabetian CP, Factor SA, Breheny PJ, Payami H. 2016. Hum Mol Genet. 25(17):3849-3862. doi: 10.1093/hmg/ddw206. PMID:27402877
Menopause accelerates biological aging. Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Ritz BR, Absher D, Assimes TL, Horvath S. Proc Natl AcadSci U S A. 113(33):9327-32. doi: 10.1073/pnas.1604558113.
Identification of Effects of Regulatory Actions on Air Quality in Goods Movement Corridors in California. Su JG, Meng YY, Pickett M, Seto E, Ritz B, Jerrett M. 2016. Environ Sci Technol. 50(16):8687-96. doi: 10.1021/acs.est.6b00926.
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease. Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL. 2016. Genome Biol. 17(1):171. doi: 10.1186/s13059-016-1030-0.
Smoking in pregnancy and risk of cancer among young children: A population-based study. Heck JE, Contreras ZA, Park AS, Davidson TB, Cockburn M, Ritz B. 2016. Int J Cancer. 139(3):613-6. doi: 10.1002/ijc.30111.
Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease. Hill-Burns EM, Ross OA, Wissemann WT, Soto-Ortolaza AI, Zareparsi S, Siuda J, Lynch T, Wszolek ZK, Silburn PA, Mellick GD, Ritz B, Scherzer CR, Zabetian CP, Factor SA, Breheny PJ, Payami H. 2016. Hum Mol Genet. pii: ddw206.
Lifetime occupational and leisure time physical activity and risk of Parkinson’s disease. Shih IF, Liew Z, Krause N, Ritz B. 2016. Parkinsonism RelatDisord. 28:112-7. doi:10.1016/j.parkreldis.2016.05.007.
Project TENDR: Targeting Environmental Neuro-Developmental Risks The TENDR Consensus Statement. Bennett D, Bellinger DC, Birnbaum LS, Bradman A, Chen A, Cory-Slechta DA, Engel SM, Fallin MD, Halladay A, Hauser R, Hertz-Picciotto I, Kwiatkowski CF, Lanphear BP, Marquez E, Marty M, McPartland J, Newschaffer CJ, Payne-Sturges D, Patisaul HB, Perera FP, Ritz B, American College of Obstetricians and Gynecologists (ACOG); Child Neurology Society; Endocrine Society; International Neurotoxicology Association; International Society for Children’s Health and the Environment; International Society for Environmental Epidemiology; National Council of Asian Pacific Islander Physicians; National Hispanic Medical Association; National Medical Association. 2016. Environ Health Perspect. 124(7):A118-22. doi: 10.1289/EHP358.
In Utero and Early-Life Exposure to Ambient Air Toxics and Childhood Brain Tumors: A Population-Based Case-Control Study in California, USA. von Ehrenstein OS, Heck JE, Park AS, Cockburn M, Escobedo L, Ritz B.
Risk of Childhood Cancer by Maternal Birthplace: A Test of the Hispanic Paradox. Heck JE, Park AS, Contreras ZA, Davidson TB, Hoggatt KJ, Cockburn M, Ritz B. 2016. JAMA Pediatr. 170(6):585-92. doi: 10.1001/jamapediatrics.2016.0097.
Multi-pollutant exposure profiles associated with term low birth weight in Los Angeles County. Coker E, Liverani S, Ghosh JK, Jerrett M, Beckerman B, Li A, Ritz B, Molitor J. 2016. Environ Int. 91:1-13. doi: 10.1016/j.envint.2016.02.011.
Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson’s Disease, California (USA). Paul KC, Sinsheimer JS, Rhodes SL, Cockburn M, Bronstein J, Ritz B. 2016. Environ Health Perspect. 124(5):570-7. doi: 10.1289/ehp.1408976.
APOE, MAPT, and COMT and Parkinson’s Disease Susceptibility and Cognitive Symptom Progression. Paul KC, Rausch R, Creek MM, Sinsheimer JS, Bronstein JM, Bordelon Y, Ritz B. 2016. J Parkinsons Dis. 6(2):349-59. doi: 10.3233/JPD-150762.
Part 3. Modeling of Multipollutant Profiles and Spatially Varying Health Effects with Applications to Indicators of Adverse Birth Outcomes. Molitor J, Coker E, Jerrett M, Ritz B, Li A; Health Review Committee. 2016. Res Rep Health Eff Inst. (183 Pt 3):3-47.
Sporadic Retinoblastoma and Parental Smoking and Alcohol Consumption before and after Conception: A Report from the Children’s Oncology Group. Azary S, Ganguly A, Bunin GR, Lombardi C, Park AS, Ritz B, Heck JE. PLoS One. 2016 Mar 18;11(3):e0151728. doi: 10.1371/journal.pone.0151728. eCollection 2016.
Of Pesticides and Men: a California Story of Genes and Environment in Parkinson’s Disease. Ritz BR, Paul KC, Bronstein JM. 2016. Curr Environ Health Rep. 3(1):40-52. doi: 10.1007/s40572-016-0083-2.
Environment and Brain Development: Challenges in the Global Context. Júlvez J, Paus T, Bellinger D, Eskenazi B, Tiemeier H, Pearce N, Ritz B, White T, Ramchandani P, Gispert JD, Desrivières S, Brouwer R, Boucher O. 2016. Neuroepidemiology. 46(2):79-82. doi: 10.1159/000442256.