Developmental and Reproductive Toxicity

The developing fetus is the most sensitive to environmental exposures which may occur through a variety of pathways. A number of COEH faculty specialize in reproductive toxicology, or teratology. Michael Collins is working on a method to determine the mechanism of action of human teratogens by detecting perturbations in the gene regulatory network of the purple sea urchin. Wendie Robbins conducts research on the potentially toxic reproductive effects of certain occupational and environmental exposures as does Beate Ritz. Patrick Allard’s laboratory examines the biological mechanisms by which plastic and pesticide chemicals lead to reproductive dysfunction and infertility.

 

Member and Associate Projects

Devaskar (PI), Jerrett (Co-I)
2015 –2019
Imaging Innovations for Placental Assessment in Response to Environmental Pollution Study Seeks to use advanced MRI techniques to assess placental insufficiency and to assess whether environmental pollution associates with insufficiency. 

 

Robbins, (PI)
RCT: Efficacy of diet and supplements for male factor infertility

 

Robbins, (PI)
Effect of Trichomonas vaginalis on human sperm motility

 

Ritz (PI), Jerrett (Co-I)
NIH    
2015 –2018
Environmental and Cognitive Decline in Older Hispanics.
Study investigates role of pesticides and air pollution in cognitive decline in older Hispanics.